Romans 11:29 For the gifts and calling of God are without repentance. KJV
“For the gifts and the calling of God are irrevocable.” NASB
“For God’s gifts and His call are irrevocable.” [He never withdraws them when once they are given, and He does not change His mind about those to whom He gives His grace or to whom He sends His call.] AMP
God had a purpose, a plan, an intention in mind for our life before the actual spiritual creation (2 Cor. 5:17) took place the moment we received Jesus. Every born again believer has passed through the creative hand of God a second time in the spiritual new creation. Ephesians 2:10 adds that we are God’s workmanship, God’s handiwork, or the product of God with an intended use.
The purpose of God is the original intent of God for our life. God calls us to this purpose (2 Tim. 1:9) and gifts us to fulfill it (Rom. 11:29). Romans 11:29 in context speaks of God’s gifts and calling of Israel but has application to all that are called and gifted. Both the gifts (notice it is plural suggesting multiple gifts) and calling (singular) is without repentance. God will not change His mind about it and it isn’t like a flawed product men sometimes make that is subject to recall. God will not recall our gifts and calling, it is irrevocable.
Fulfilling one’s purpose is not automatic. It does not just happen once we are saved. It requires commitment and effort. We have to want to, decide to, and make an effort to fulfill our purpose. We must not be double minded (James 1:8) or have a “back door,” a “bridge of retreat,” and an “escape clause” in our commitment to fulfilling our purpose. When we face obstacles or when things don’t go right, we cannot allow ourselves to find “a message from God” or “leading from God” that somehow enables us to conclude God’s changed His mind (repented), altered, or recalled our purpose. People who do this often say things like, “I feel lead,” “my time is up,” “it’s time to move on,” or “it’s just not working for me here.” Double minded people make thousands of excuses which are simply bridges of retreat or a subtle way to say they want released from their commitment.
We need reassured at the times when we are tempted to retreat from our commitment that God is for us and if God is for us who can be against us (Rom. 8:31) The purpose for which we are called and predestined to walk out is why God will make all things work together for our good (Rom. 8:28-30). He is committed to His purpose and to help us fulfill it. Phil 1:6 says, “Being confident of this very thing, that he which hath begun a good work in you will perform it until the day of Jesus Christ.”
Pastor John Rasicci is the founder and Pastor of Word of His Grace Church in Cuyahoga Falls, Ohio, where we are building people who are building the Church. Pastor's ministry mission is to help people discover God's dream for their Life, the Local Church, and the Last Days' Harvest. With a strong emphasis on the grace of God and with a prophetic voice, Pastor John preaches and teaches in churches, conferences, and crusades both locally and throughout the world. He has produced books, tapes, and other teaching materials to empower, enable, and equip Believers with the Word of God. Pastor John is married to his wife Candy who with their three children, Krista, Joanna, John Anthony, and two son-in-laws, Matt and Doug, serve together in the ministry. After graduating from Kent State University, Pastor John pursued a career in professional baseball before accepting the call to the ministry. He and his wife, Candy, received their ministry training from Rhema Bible Training Center in Tulsa, Oklahoma.
John Rasicci 
Great explanation Preacher!